Is there still a place for significance testing in clinical trials?

I’ve spent a lot of time thinking about hypothesis tests in clinical trials recently. Periodically, it’s good to question the fundamentals of whether this is a good idea in general. I don’t think my views have changed. I was considering writing a blog post but then I came across this article by the editors of the Clinical Trials journal which pretty much sums it up. The article can also be found with DOI: 10.1177/1740774519846504.

Dominic Magirr
Medical Statistician

Interested in the design, analysis and interpretation of clinical trials.