Posts

The MaxCombo Test severely inflates the type 1 error rate

“The MaxCombo Test severely inflates the type 1 error rate”, by Carl-Fredrik Burman and myself has just been published in JAMA …
Last updated on Oct 17, 2022 9 min read

{nphRCT} on CRAN

I’m delighted that our new R package {nphRCT} is available on CRAN. Special thanks to Isobel Barrot. Her R skills have made this …
Last updated on Sep 1, 2022 6 min read

Pseudo-observations 2

This is a quick follow up to my previous post on pseudo-observations where I reproduced Table 1 from “Causal inference in survival …
Last updated on Jul 4, 2022 5 min read

Pseudo observations on pseudo-observations

Idea / motivation I’ve set myself the challenge of reproducing the results in Table I of “Causal inference in survival analysis using …
Last updated on Jul 1, 2022 9 min read

Conditional and unconditional treatment effects in RCTs

Small simulation study Quick function to simulate data from an RCT with equal allocation to treatments 0 and 1, a single covariate, and …
Last updated on May 25, 2022 4 min read

What's the difference between fixed, random, independent, type I, type II, (non)prognostic, (non)ignorable, and (non)informative censoring?

I already feel exhausted after writing the title. I’m not really going to explain all these differences, sorry. I’m not capable. And …
Last updated on Jan 19, 2022 4 min read

Be careful with standard errors in `survival::survfit`

(Mild) panic In my previous post I looked into how survival::survfit produces standard errors and confidence intervals for a survival …
Last updated on Jan 18, 2022 5 min read clinical trials, survival analysis

Confidence interval for a survival curve based on a Cox model

A colleague caught me out recently when they asked about a confidence interval for a survival curve based on a Cox model. This can be …
Last updated on Jan 17, 2022 6 min read survival analysis

Notes on concordance

Motivation I don’t understand the details of concordance in survival analysis, so I’m trying to explain it to myself. Probabilistic …
Last updated on Dec 14, 2021 16 min read

Trouble with tau

This post is to express some minor frustration with some papers I’ve read recently evaluating the performance of restricted mean …
Last updated on Oct 15, 2021 4 min read survival analysis, clinical trials